Effects of Chemical and Biological Anti-mycotoxins on Performance, Haematological, Biochemical and Immunological Parameters of Broiler Chickens during Aflatoxicosis

Document Type : Original Article

Authors

1 Department of Clinical Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt

2 Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt

3 Department of Animal Hygiene, Zoonosis, and Behavior, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt

4 Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt

Abstract

Background:Contamination of feedstuffs with mycotoxins is a worldwide problem of great importance. Mycotoxins are secondary toxic fungal metabolites. There are great interests to create effective prevention and decontamination methods to diminish the toxic effects of AFs in animal and poultry production.
Objectives: The present study was designed to evaluate the toxic effects of aflatoxin on performance, some hematological, serum biochemical and immunological parameters and to determine the preventive effect of added anti-mycotoxins.
Methods:In this study, a total of 180 broilers were used and divided into 6 equal groups. They received zeocem (chemical synthetic anti-mycotoxin) at a dose of 1 kg/ton feed and nutritox (biological synthetic anti-mycotoxin) at a dose of 0.25 kg/ton feed, to treat broiler fed aflatoxin. All treatments were administered from 1- 42 days of age.
Results: By the end of the experiment, nutritox (biological synthetic anti-mycotoxin) alleviated the hazardous effects of aflatoxin on performance, hematological, serum biochemical and immunological parameters rather than zeocem (chemical anti-mycotoxin) fed broilers.
Conclusion:Treatment with biological synthetic anti-mycotoxin (nutritox) is better than using chemical synthetic anti-mycotoxin (zeocem) in control of aflatoxicosis in broilers.

Keywords