Mosquito Larvicidal and Pupicidal Potential of Heliotropium curassavicum L. Against Culex pipiens (Diptera: Culicidae) and Their Chemical Composition in Kingdom of Saudi Arabia

Y., El-Kholy M.; Musa, Arafa

doi:10.21608/eajbsf.2015.17240

Mosquito Larvicidal and Pupicidal Potential of Heliotropium curassavicum L. Against Culex pipiens (Diptera: Culicidae) and Their Chemical Composition in Kingdom of Saudi Arabia

Document Type : Original Article

Authors

El-Kholy M. Y. ¹
Arafa Musa ²

¹ -Department of Biology, College of Science, Aljouf University, Sakaka, Aljouf, Kingdom of Saudi Arabia. -Department of Pests and Plant Protection, National Research Centre, Dokki, Cairo, Egypt

² -Department of Pharmacognosy, College of Pharmacy, Aljouf University, Sakaka, Aljouf, Kingdom of Saudi Arabia. -Department of Pharmacognosy, College of pharmacy, Al-Azhar University, Cairo, Egypt

10.21608/eajbsf.2015.17240

Abstract

Curassavine was isolated as a yellowish viscous liquid and identified as (ester of trachelanthamidine and 3-carboxy-4-methylhexane-2,3-diol) by the aid of mass spectrometry (MS) and Nuclear Magnetic Resonance spectroscopy (¹H and ¹³C-NMR).Considerable mortality was evident after the treatment. With regard to the larvicidal activity, the obtained data showed mortality percentages between 4 and 24 % using concentrations between 100 and 500 mg/ml after 3 days. The mortality increased to reach 8 and 86 % for the same concentrations within 5 days. LC₅₀ was 288.4 mg/ml. Concerning the pupicidal activity, no effect using concentrations between 100 and 500 mg/ml within 2 days; while they showed mortality percentages between 8 and 60 % within 5 days. LC₅₀ was 512.9 mg/ml. On the other hand, Curassavine caused mortality percentages among larvae and pupae of Culex pipiens between 12 and 84 % using concentrations between 100 and 500 µg/ml after one day. While they showed mortality percentages between 16 and 100 % within 2 days; Value of LC₅₀ was 147.9 µg/ml.

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